specialist in digestive health since 2008

specialist in digestive health since 2008

Since 2008, we’ve dedicated ourselves to crafting nutritional supplements. Our team of dieticians meticulously develops our products with exceptional care. We prioritize purity, using only essential ingredients in our formulations. This guarantees our supplements are gluten-free, soy-free, and of superior quality, ensuring safety and minimizing unwanted side effects.

low FODMAP Certified™ by the Monash University

low FODMAP Certified™ by the Monash University

Our products proudly hold the Low FODMAP Certified™ status from Monash University

more than 100,000 satisfied customers

more than 100,000 satisfied customers

Since 2008, our mission has been to “help everyone enjoy their food again.” We are proud to have supported over 100,000 customers.

Best antihistamine for histamine intolerance

When searching for effective ways to manage histamine intolerance, it’s important to consider factors that address the root cause of symptoms. Histamine intolerance occurs when the body struggles to break down histamine, often due to low levels of the enzyme diamine oxidase (DAO). Understanding DAO’s role and how it differs from traditional antihistamines is essential for making an informed choice.

The role of DAO in histamine intolerance

DAO is a naturally occurring enzyme primarily responsible for breaking down dietary histamine in the digestive system. When DAO levels are insufficient, histamine accumulates in the body, leading to symptoms such as headaches, skin rashes, bloating, and gastrointestinal discomfort. Unlike traditional antihistamines, which block histamine receptors to alleviate symptoms, DAO supplements work by reducing histamine levels directly. This makes DAO supplements a valuable option for those with histamine intolerance caused by enzyme deficiency.

Understanding HDUs and enzyme activity

For those considering DAO supplements, the enzyme’s activity level is a critical factor in selecting the right product. This is typically measured in Histamine Degrading Units (HDUs), a standardized metric that quantifies the enzyme’s capacity to break down histamine. A higher HDU value indicates greater potency, providing a clearer indication of a product’s effectiveness. Look for supplements with transparent labeling of HDU values and enzyme concentrations to ensure you’re choosing a high-quality option tailored to your needs. An example is DAO Mini. DAO mini contains 30,000 HDU which is a lot higher than most of its competitors.

Antihistamines vs. DAO supplements

While DAO supplements target the enzymatic breakdown of histamine, traditional antihistamines (such as H1 or H2 receptor blockers) work by preventing histamine from binding to its receptors. These medications are often used to manage acute allergic reactions or symptoms unrelated to histamine intolerance. In contrast, DAO supplements address the root cause of histamine intolerance, offering a complementary or alternative approach for long-term symptom management. For individuals with histamine intolerance, combining DAO supplements with dietary adjustments—such as reducing high-histamine foods—can significantly improve outcomes.

Additional considerations

When exploring solutions for histamine intolerance, it’s important to evaluate individual factors such as sensitivities to medications or supplements. Some people may experience intolerance to antihistamines or inactive ingredients in supplements. Consulting a healthcare professional can help you identify the most suitable approach, balancing symptom relief with safety and overall health.

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