specialist in digestive health since 2008

specialist in digestive health since 2008

We have been developing and producing nutritional supplements since 2008. Our products are specially developed with great care and attention by our in-house dieticians. For the composition of our products we use only necessary ingredients, so our products are pure, free of gluten and soy and of high quality. This ensures that our supplements can be used safely and without adverse side effects. Our products are low FODMAP Certified™ by Monash University.

free dietary advice

free dietary advice

Our team of specialized dietitians is always at your service with practical advice and additional information about our products. Contact us via:

Chat: for quick and direct personal advice

Mail: info@intoleran.com

Phone: +31302272172

more than 100,000 satisfied customers

more than 100,000 satisfied customers

Since 2008, our mission is to help everyone enjoy their food. We are proud to support over 100,000 customers already.

Histamine

Histamine

Histamine is a biogenic amine (natural protein) that is involved in a number of processes in the body. For example, histamine plays a role in the gastrointestinal tract, the central nervous system, lungs, sleep system and the immune system. Histamine is largely stored in mast cells. Mast cells are specialised cells found in tissues in contact with the outside world such as skin, lungs and gastrointestinal tract.

Allergic reactions release histamine. Medicines can also cause histamine to be released. Histamine is also found in the brain where it plays a role in the transmission of signals (neurotransmitter). Histamine is involved in the sleep-wake rhythm, among other things. That is why some anti-hay fever medicines (antihistamines) make you drowsy. An excess of Histamine will make you very alert and watchful, resulting in sleeplessness. Histamine is involved in many more processes, such as the production of gastric acid, the diameter and permeability of blood vessels (blood pressure) and the increase of adrenalin (nervous feeling).

Histamine is not only important for humans but also for animals and plants. That is why histamine occurs naturally in both plant and animal food. Processed food also has a significantly higher histamine content. Examples are ready meals, cheese, ham, sausages and (smoked) fish. Because histamine is formed during processes of deterioration, food that has been lying around for a while also has a higher histamine content. Unfortunately the substance is not broken down during cooking, so the histamine level will not (almost) change.

But also processed drinks like wine (especially sparkling wine) and (non-alcoholic) beer are best avoided if you are sensitive to histamine. In addition to containing histamine, these drinks also release histamine in the body.

Remember two important generalities:

  • Fresh produce contains less histamine than processed or aged produce.
  • Processed products contain more histamine than unprocessed products.

Our products

DAO Plus

50 Capsules
  • Contains the enzyme Diamine Oxidase (DAO)
  • Supplemented with vitamin C and quercetin
  • Suitable for children 4 years and older

DAO Mini

Dispenser 60 Tablets
  • Contains the pure enzyme Diamine Oxidase (DAO)
  • Small tablet, ideal for children
  • In easy-to-bring portable dispenser

Fructase

36 Capsules
  • Contains the digestive enzyme xylose isomerase
  • Pure composition and vegan ingredients
  • Low FODMAP Certified™ by Monash University

Quatrase 10,000 (Forte)

36 Capsules
5/5
  • Special blend of digestive enzymes
  • Helps digest complex carbohydrates
  • Reduces the risk of gas formation*
  • Pure composition and vegan ingredients

Starchway

50 Capsules
  • Special blend of digestive enzymes
  • Pure composition and vegan ingredients
  • Low FODMAP Certified™ by Monash University

Fibractase Forte (1200)

36 Capsules
  • Helps digest complex carbohydrates
  • Reduces the risk of gas formation*
  • Pure composition and vegan ingredients

Lactase 20,000

50 Scored Tablets
  • Highest dosed lactase tablet
  • Ideal for large quantities of lactose
  • Pure composition and vegan ingredients
dietitian intoleran

Free advice from our dietitians

Do you have questions about our products? Feel free to contact us. One of our dietitians will help you find the supplement that fits your needs best.

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