diamine oxidase (DAO)

the enzyme diamine oxidase (DAO)

Diamine oxidase (DAO) is the body’s own enzyme that can digest histamine from food in the small intestine. Diamine oxidase is also present in the kidneys and the placenta. The diamine oxidase enzyme contained in our DAO supplements is derived from porcine kidney protein extract.

Unfortunately, no plant-based version of the enzyme is available (yet). Research has been done, but with the current technology it is still a step too far, as the shelf life of the plant-based enzyme is only a few weeks.

Diamine oxidase helps to digest the histamine that is naturally present in food. This histamine is called exogenous histamine. Because the exogenous histamine is digested in the small intestine it cannot migrate through the gastrointestinal wall into the bloodstream and increase histamine levels there.

The histamine in the body is called endogenous histamine. An excessively high level of endogenous histamine can cause histamine intolerance symptoms.

our products

DAO plus – 50 capsules

histamine intolerance

Capsules containing the enzyme Diamine Oxidase (DAO), vitamin C and Quercetin. DAO plus is complete and effective. 

DAO & cozidase

DAO mini – dispenser 60 tablets

histamine intolerance

Tablets containing the enzyme Diamine Oxidase (DAO). DAO mini is pure and efficient.

DAO & cozidase

fructase – 36 capsules

fructose intolerance

Capsules with the enzyme Xylose Isomerase


quatrase forte – 36 capsules


Capsules containing four different enzymes to aid the digestion of various FODMAPs such as lactose. Ideal for the consumption of large amounts of FODMAPs.


starchway – 50 capsules

starch and sucrose intolerance

Capsules containing the enzymes Invertase and Gluco-Amylase.


fibractase forte – 36 capsules

fructan and galactan intolerance

Capsules containing the enzyme Alpha Galactosidase.


lactase 20,000 – 50 scored tablets

lactose intolerance

This product is the highest lactase dosage tablet we supply. It is ideal if you are very sensitive to lactose or when consuming large amounts of lactose from food.


free advice from our dietitians

Do you have questions about our products? Feel free to contact us. One of our dietitians will help you find the supplement that fits your needs best.

intoleran employees
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