The amount of the active Diamine Oxidase enzyme is the same in both products, 20,000 - 30,000 HDU per tablet/capsule. If you want to use only the Diamine Oxidase enzyme, you should choose the DAO mini tablets. These are easy to swallow (5mm diameter). If you also want the benefits of the additional active ingredients Vitamin C and Quercetin, choose the DAO plus. If would like to spread out the quantity of DAO enzyme during your day then it's possible to open up your recommended dose of 3 capsules and just take the small beige DAO tablets multiple times a day. That way you can still adhere to the maximum dose of 3 capsules a day but are able to take smaller dosages of the DAO enzyme.